Gut Bacteria Capsules

A healthy gut is the foundation for your wellbeing and a strong immune defence. Problems in the gut can therefore affect our entire body and lead to many different diseases and symptoms.

Hippocrates knew this too, who 2500 years ago postulated:

"The gut is the father of all suffering"

Modern scientific research also confirms this statement. There is substantial evidence that chronic inflammatory diseases, which include metabolic disorders such as diabetes, autoimmune diseases such as multiple sclerosis, and also neuroinflammatory diseases such as depression or ME/CFS, have their origin in the gut (1).

An important role is played by the so-called microbiome. This is the totality of all microorganisms, such as bacteria, viruses and fungi, that naturally live in and on our body. They are particularly abundant in the gut. These microorganisms help with digestion, support the immune system and contribute to protection against harmful pathogens. A balanced microbiome is therefore important for our health, as it influences many processes in the body.

Factors such as stress, an unbalanced diet or antibiotics can disrupt the delicate microbiome in the gut. This is exactly where probiotics come in: they help to restore the natural balance in the gut.

Probiotics are living microorganisms, usually bacteria or yeasts, that occur naturally in certain foods or are taken as dietary supplements. They are also found in fermented products such as yoghurt, sauerkraut or kefir.

With apple fibre powder, a prebiotic, our gut bacteria capsules also provide the right food for the good bacteria.

Our gut bacteria capsules provide you with a carefully selected mixture of seven probiotic bacterial strains that specifically promote your gut health.

Lactobacillus plantarum: Clinical studies have shown that this strain regulates innate and acquired cellular and humoral immunity (2). Particularly interesting for athletes: L. plantarum was able to alleviate oxidative stress after a triathlon by increasing anti-inflammatory IL-10 and reducing pro-inflammatory factors such as TNF-α, IL-6 and IL-8 (3).

Lactobacillus reuteri: This strain is known for its diverse health benefits, including promoting gastrointestinal health, modulating the immune system and inhibiting the growth of pathogenic microorganisms. L. reuteri produces reuterin, an antimicrobial substance that plays an important role in maintaining a healthy microbial balance in the gut (4).

Bifidobacterium adolescentis: These bacteria can help with fat loss and provide better glucose tolerance. A study in the high-quality journal Nature Metabolism showed that consuming resistant starch helped proliferate B. adolescentis, which ultimately made the participants metabolically healthier (5).

Streptococcus thermophilus: A probiotic bacterial strain commonly used in the dairy industry, particularly in the production of yoghurt and cheese. It is known for its ability to convert lactose into lactic acid, which is particularly beneficial for people with lactose intolerance. Furthermore, S. thermophilus was able to improve symptoms of osteoarthritis by producing hyaluronic acid and slow the progression of joint damage (6).

Bifidobacterium lactis: With over 200 clinical studies, it is one of the most thoroughly researched bifidobacteria worldwide. One of these studies looked at antibiotic-associated disruptions of gut flora and found that administration of B. lactis could restore the acetate content in stool to baseline levels after 30 days, which was not the case in the control group. Acetate, a short-chain fatty acid, is important for maintaining an acidic gut environment (7).

Bifidobacterium longum: This strain can help relieve irritable bowel syndrome symptoms. In a clinical study, administration of B. longum improved gastrointestinal symptoms in IBS patients with diarrhoea. Interestingly, not only living bacteria but also heat-killed strains of B. longum were able to improve symptoms (8). B. longum also has a positive influence on sleep quality and stress (9).

Bifidobacterium infantis: This strain was originally found in the gut of infants, which also gave it its name. But adults can also benefit from it. Administration of B. infantis in patients with inflammatory diseases (ulcerative colitis, chronic fatigue syndrome and psoriasis) reduced the inflammatory marker CRP compared to placebo (10).

Whether you have specific complaints or simply want to optimise or maintain your gut health – our gut bacteria take care of it.

Sources:

1. Fasano A. All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases. F1000Research. 31 January 2020;9:F1000 Faculty Rev-69.

2. Zhao W, Peng C, Sakandar HA, Kwok LY, Zhang W. Meta-Analysis: Randomized Trials of Lactobacillus plantarum on Immune Regulation Over the Last Decades. Front Immunol. 22 March 2021;12:643420.

3. Huang HY, Tsao SP. Long Term Supplementation of Lactobacillus plantarum PS128 Attenuated High-Intensity Exercise Induced Acute-Phase Inflammation in Triathletes. Curr Dev Nutr. 29 May 2020;4(Suppl 2):1564.

4. Cleusix V, Lacroix C, Vollenweider S, Duboux M, Le Blay G. Inhibitory activity spectrum of reuterin produced by Lactobacillus reuteri against intestinal bacteria. BMC Microbiol. 12 November 2007;7:101.

5. Li H, Zhang L, Li J, Wu Q, Qian L, He J, u. a. Resistant starch intake facilitates weight loss in humans by reshaping the gut microbiota. Nat Metab. 26 February 2024;1–20.

6. Lyu JL, Wang TM, Chen YH, Chang ST, Wu MS, Lin YH, u. a. Oral intake of Streptococcus thermophilus improves knee osteoarthritis degeneration: A randomized, double-blind, placebo-controlled clinical study. Heliyon. 25 April 2020;6(4):e03757.

7. Merenstein D, Fraser CM, Roberts RF, Liu T, Grant-Beurmann S, Tan TP, u. a. Bifidobacterium animalis subsp. lactis BB-12 Protects against Antibiotic-Induced Functional and Compositional Changes in Human Fecal Microbiome. Nutrients. 17 August 2021;13(8):2814.

8. Srivastava S, Basak U, Naghibi M, Vijayakumar V, Parihar R, Patel J, u. a. A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live Bifidobacterium longum CECT 7347 (ES1) and heat-treated Bifidobacterium longum CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome. Gut Microbes. 16(1):2338322.

9. Patterson E, Tan HTT, Groeger D, Andrews M, Buckley M, Murphy EF, u. a. Bifidobacterium longum 1714 improves sleep quality and aspects of well-being in healthy adults: a randomized, double-blind, placebo-controlled clinical trial. Sci Rep. 14 February 2024;14(1):3725.

10. Groeger D, O'Mahony L, Murphy EF, Bourke JF, Dinan TG, Kiely B, u. a. Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut. Gut Microbes. 12 July 2013;4(4):325–39.