{"product_id":"piperin","title":"Piperine","description":"\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eWhat is piperine? \u003c\/span\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003ePepper has traditionally been used for a long time as a versatile spice and has served not only the function of improving the flavour of dishes. It was used to extend the shelf life of food, but was also considered to aid digestion, warm and anti-inflammatory. \u003c\/span\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003ePiperine is a main ingredient in pepper and the reason for the sharp taste of the spice. In modern studies, the diverse health-promoting effects of pepper have also been confirmed for piperine. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eThese are the benefits of piperine\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThe most well-known effect of piperine is the ability as a \u003c\/span\u003e\u003cspan\u003ebioenhancer\u003c\/span\u003e\u003cspan\u003e to increase the bioavailability of other nutrients. An often-used combination is the addition of piperine or pepper to turmeric dietary supplements. Piperine supports the absorption of the turmeric active ingredient curcumin. \u003c\/span\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eStudies also showed increased vitamin, Q10 and beta-carotene absorption through piperine. (Badmaev et al., 2000)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThe reason for better bioavailability is a combination of faster absorption and slower elimination of the substances. Through piperine, a substance like curcumin can thus be very quickly absorbed through the intestinal barrier, since piperine increases the permeability of the intestinal barrier. (Khajuria et al., 2002)\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eFurthermore, piperine inhibits various degradation enzymes in the liver and intestine. This allows the active ingredients to remain longer in the body and can achieve stronger effects. (Singh et al., 1986\u003c\/span\u003e\u003cspan\u003e)\u003c\/span\u003e\u003cspan\u003e Piperine can further inhibit efflux transporters. These have the task of transporting substances like drugs out of the cells. Through piperine, their activity is reduced and the active ingredients can remain longer in the cells and work. (Chavarria et al., 2016) \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eApart from its bioenhancer function, piperine had the following effects in animal studies: \u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cspan\u003eReduction of blood pressure (Taqvi et al., 2008) \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cspan\u003eAntidepressive effect. (Wattanathorn et al., 2008) \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\" dir=\"ltr\"\u003e\n\u003cp role=\"presentation\" dir=\"ltr\"\u003e\u003cspan\u003eSuppression of body fat accumulation from very high-fat diet (Okumura et al., 2010)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cspan\u003eWhat distinguishes the piperine capsules? \u003c\/span\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThe edubily piperine capsules are simple to use and can be taken as a universal bioenhancer with all dietary supplements to increase the absorption rate of ingredients. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eFor our piperine capsules, we use BioPerine®, which can increase the absorption of nutrients by at least 30%. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eUnlike black pepper, pure BioPerine® works directly and thus offers a great advantage in absorption. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eNaturally, the product is vegan in its composition.\u003c\/span\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003ch3 dir=\"ltr\"\u003eStudies on piperine\u003c\/h3\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e(Badmaev et al., 2000) PMID: \u003c\/span\u003e\u003cspan\u003e10715596) \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e(Khajuria et al., 2002) https:\/\/doi.org\/10.1078\/0944-7113-00114 \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e(Singh et al., 1986\u003c\/span\u003e\u003cspan\u003e) \u003c\/span\u003e\u003cspan\u003ePMID: 3080587\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e(Chavarria et al., 2016) PMID: 26560940\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e(Taqvi et al., 2008) PMID: 19033825) \u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e(Wattanathorn et al., 2008) PMID: \u003c\/span\u003e\u003cspan\u003e18639606\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e(Okumura et al., 2010) \u003c\/span\u003e\u003cspan\u003e\u003cspan class=\"Apple-tab-span\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003ca href=\"https:\/\/doi.org\/10.1271\/bbb.100117\"\u003e\u003cspan\u003ehttps:\/\/doi.org\/10.1271\/bbb.100117\u003c\/span\u003e\u003c\/a\u003e\u003cb\u003e\u003cbr\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThe data obtained in this way suggest that piperine is very quickly absorbed through the intestinal barrier. It can act as a nonpolar molecule and form nonpolar complexes with drugs and dissolved substances. It can modulate membrane dynamics due to its easy distributability and thus contribute to efficient permeability through the barrier. PMID: \u003c\/span\u003e\u003cspan\u003e9536651\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"edubily GmbH","offers":[{"title":"Default Title","offer_id":50433053983046,"sku":"EDU-162","price":18.0,"currency_code":"CHF","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/piperin_1_1.png?v=1736698771","url":"https:\/\/www.edubily.ch\/en\/products\/piperin","provider":"edubily Schweiz ","version":"1.0","type":"link"}