{"product_id":"l-carnosin","title":"PURE L-Carnosine Capsules","description":"\u003ch2\u003eWhat is Carnosine?\u003c\/h2\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eCarnosine is a dipeptide, which is a substance that \u003cstrong\u003econsists of two amino acids: Beta-Alanine and L-Histidine\u003c\/strong\u003e. Carnosine was discovered over 100 years ago in meat extract and is therefore nothing new. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eMethyl groups can be attached to carnosine. These methylated carnosine forms are anserine and ophidine.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003cstrong\u003eCarnosine and its methylated forms are found exclusively in meat\u003c\/strong\u003e – neither in plants nor in fungi has carnosine or derived substances been discovered. Particularly high amounts of carnosine are found in the muscle tissue of poultry, buffalo, horse, beef and pork. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIn both animals and humans, carnitine is found almost exclusively in skeletal muscle (up to 99 % of the total occurrence in the organism).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIn principle, the body can produce carnosine itself, namely from the precursors Beta-Alanine and Histidine, mediated by an enzyme called Carnosine Synthase (CS). However, it has been shown that the Beta-Alanine amounts produced this way are not sufficient to adequately support carnosine synthesis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eAn \u003cstrong\u003eexogenous supply of Beta-Alanine or preferably directly L-Carnosine is therefore necessary\u003c\/strong\u003e to increase the muscular carnosine stores. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 data-mce-fragment=\"1\"\u003e\u003cstrong\u003eWhat does Carnosine do?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eCarnosine can generally act as an \u003cstrong\u003eacid buffer in muscle\u003c\/strong\u003e and also possesses the ability to bind divalent metals such as copper, zinc, cobalt, nickel or cadmium. Furthermore, it is a \u003cstrong\u003epowerful antioxidant\u003c\/strong\u003e, which is in no way inferior to vitamin E and vitamin C in neutralising superoxide anions. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eAlso very potent is the effect of carnosine against AGEs (\u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eadvanced glycation end-products\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e) and ALEs (\u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eadvanced lipoxidation end-products\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e). These substances form through the reaction of sugars and fats with proteins and play a role in ageing and in the development of many diseases.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eStudies show a variety of positive effects of carnosine:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eBeta-Alanine, the precursor of carnosine, has long been known in the sports field. By increasing carnosine stores, acids that build up in the muscle during exertion can be better buffered. In a randomised, controlled human study, this acid-reducing effect of Beta-Alanine during high-intensity exercise could be confirmed. (\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e1)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIn a gold-standard study on diabetics, administration of 1 g of carnosine per day within 12 weeks led to a \u003cstrong\u003esignificant decrease in fat mass as well as improvement in some diabetes-associated blood markers\u003c\/strong\u003e. (\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e2)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIn 2024, this positive effect on blood sugar regulation could again be confirmed in a randomised clinical study, in which daily administration of carnosine could \u003cstrong\u003ereduce blood sugar elevation within the scope of a glucose tolerance test\u003c\/strong\u003e. (\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e3)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIn diabetic nephropathy, a kidney damage caused by persistently elevated blood sugar levels, carnosine in an RCT study (\u003c\/span\u003e\u003ci data-mce-fragment=\"1\" style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\u003cspan data-mce-fragment=\"1\" data-mce-style=\"font-weight: 400;\"\u003erandomised clinical trial\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e) could inhibit the formation of a growth factor that contributes to kidney damage and could thus exert a \u003cstrong\u003ekidney-protective effect in diabetes\u003c\/strong\u003e. (\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e4)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eThe intake of carnosine also appears to have a positive effect on depression in clinical studies: subjects who took carnosine in addition to an antidepressant experienced a \u003cstrong\u003estronger antidepressive effect\u003c\/strong\u003e as well as a higher remission rate than the placebo group. (\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e5)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eA mixture of carnosine and its derivative methylcarnosine (anserine) showed positive effects in a further clinical study in healthy elderly people who already showed \u003cstrong\u003emild cognitive impairment\u003c\/strong\u003e, a precursor to dementia. The (methyl-)carnosine group achieved a better score in the \u003c\/span\u003e\u003ci data-mce-fragment=\"1\" style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003eGlobal Clinical Dementia Rating\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e compared to placebo. The improvement was particularly pronounced in carriers of the \"Alzheimer gene\" ApoE4. (\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e6)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\u003c\/ul\u003e\n\u003ch2 data-mce-fragment=\"1\"\u003e\u003cstrong\u003eL-Carnosine from the PURE range\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIn our product, we use \u003cstrong\u003epure L-Carnosine\u003c\/strong\u003e in an ideal dosage. As always with PURE products, no additional substances are included. Our L-Carnosine is ideally suited to \u003cstrong\u003ereplenish the body's stores\u003c\/strong\u003e and thus to enjoy the many benefits of carnosine.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eSources\u003c\/span\u003e\u003c\/p\u003e\n\u003col data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e \u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eBaguet, A., Koppo, K., Pottier, A. \u0026amp; Derave, W. Beta-Alanine supplementation reduces acidosis but not oxygen uptake response during high-intensity cycling exercise. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eEur. J. Appl. Physiol. \u003c\/span\u003e\u003c\/i\u003e\u003cb data-mce-fragment=\"1\"\u003e108\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e, 495–503 (2010).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e \u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eHoujeghani, S., Kheirouri, S., Faraji, E. \u0026amp; Jafarabadi, M. A. l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumour necrosis factor-α levels in patients with type 2 diabetes: a double-blind placebo-controlled randomised clinical trial. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eNutr. Res. N. Y. N \u003c\/span\u003e\u003c\/i\u003e\u003cb data-mce-fragment=\"1\"\u003e49\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e, 96–106 (2018).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e \u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eHariharan, R. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eet al.\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e Carnosine supplementation improves glucose control in adults with pre-diabetes and type 2 diabetes: A randomised controlled trial. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eNutr. Metab. Cardiovasc. Dis. \u003c\/span\u003e\u003c\/i\u003e\u003cb data-mce-fragment=\"1\"\u003e34\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e, 485–496 (2024).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e \u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eSiriwattanasit, N., Satirapoj, B. \u0026amp; Supasyndh, O. Effect of Oral carnosine supplementation on urinary TGF-β in diabetic nephropathy: a randomised controlled trial. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eBMC Nephrol. \u003c\/span\u003e\u003c\/i\u003e\u003cb data-mce-fragment=\"1\"\u003e22\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e, 236 (2021).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e \u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eAraminia, B. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eet al.\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e L-Carnosine combination therapy for major depressive disorder: A randomised, double-blind, placebo-controlled trial. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eJ. Affect. Disord. \u003c\/span\u003e\u003c\/i\u003e\u003cb data-mce-fragment=\"1\"\u003e267\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e, 131–136 (2020).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e \u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eMasuoka, N. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eet al.\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e Effects of Anserine\/Carnosine Supplementation on Mild Cognitive Impairment with APOE4. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eNutrients \u003c\/span\u003e\u003c\/i\u003e\u003cb data-mce-fragment=\"1\"\u003e11\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e, 1626 (2019).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"edubily®","offers":[{"title":"Default Title","offer_id":50433082360134,"sku":"EDU-150","price":34.5,"currency_code":"CHF","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/L-Carnosin.png?v=1726221732","url":"https:\/\/www.edubily.ch\/en\/products\/l-carnosin","provider":"edubily Schweiz ","version":"1.0","type":"link"}