{"title":"Amino Acids","description":"","products":[{"product_id":"l-carnosin","title":"PURE L-Carnosine Capsules","description":"\u003ch2\u003eWhat is Carnosine?\u003c\/h2\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eCarnosine is a dipeptide, which is a substance that \u003cstrong\u003econsists of two amino acids: Beta-Alanine and L-Histidine\u003c\/strong\u003e. Carnosine was discovered over 100 years ago in meat extract and is therefore nothing new. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eMethyl groups can be attached to carnosine. These methylated carnosine forms are anserine and ophidine.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003cstrong\u003eCarnosine and its methylated forms are found exclusively in meat\u003c\/strong\u003e – neither in plants nor in fungi has carnosine or derived substances been discovered. Particularly high amounts of carnosine are found in the muscle tissue of poultry, buffalo, horse, beef and pork. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIn both animals and humans, carnitine is found almost exclusively in skeletal muscle (up to 99 % of the total occurrence in the organism).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIn principle, the body can produce carnosine itself, namely from the precursors Beta-Alanine and Histidine, mediated by an enzyme called Carnosine Synthase (CS). However, it has been shown that the Beta-Alanine amounts produced this way are not sufficient to adequately support carnosine synthesis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eAn \u003cstrong\u003eexogenous supply of Beta-Alanine or preferably directly L-Carnosine is therefore necessary\u003c\/strong\u003e to increase the muscular carnosine stores. \u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 data-mce-fragment=\"1\"\u003e\u003cstrong\u003eWhat does Carnosine do?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eCarnosine can generally act as an \u003cstrong\u003eacid buffer in muscle\u003c\/strong\u003e and also possesses the ability to bind divalent metals such as copper, zinc, cobalt, nickel or cadmium. Furthermore, it is a \u003cstrong\u003epowerful antioxidant\u003c\/strong\u003e, which is in no way inferior to vitamin E and vitamin C in neutralising superoxide anions. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eAlso very potent is the effect of carnosine against AGEs (\u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eadvanced glycation end-products\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e) and ALEs (\u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eadvanced lipoxidation end-products\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e). These substances form through the reaction of sugars and fats with proteins and play a role in ageing and in the development of many diseases.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eStudies show a variety of positive effects of carnosine:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eBeta-Alanine, the precursor of carnosine, has long been known in the sports field. By increasing carnosine stores, acids that build up in the muscle during exertion can be better buffered. In a randomised, controlled human study, this acid-reducing effect of Beta-Alanine during high-intensity exercise could be confirmed. (\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e1)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIn a gold-standard study on diabetics, administration of 1 g of carnosine per day within 12 weeks led to a \u003cstrong\u003esignificant decrease in fat mass as well as improvement in some diabetes-associated blood markers\u003c\/strong\u003e. (\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e2)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIn 2024, this positive effect on blood sugar regulation could again be confirmed in a randomised clinical study, in which daily administration of carnosine could \u003cstrong\u003ereduce blood sugar elevation within the scope of a glucose tolerance test\u003c\/strong\u003e. (\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e3)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIn diabetic nephropathy, a kidney damage caused by persistently elevated blood sugar levels, carnosine in an RCT study (\u003c\/span\u003e\u003ci data-mce-fragment=\"1\" style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003e\u003cspan data-mce-fragment=\"1\" data-mce-style=\"font-weight: 400;\"\u003erandomised clinical trial\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e) could inhibit the formation of a growth factor that contributes to kidney damage and could thus exert a \u003cstrong\u003ekidney-protective effect in diabetes\u003c\/strong\u003e. (\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e4)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eThe intake of carnosine also appears to have a positive effect on depression in clinical studies: subjects who took carnosine in addition to an antidepressant experienced a \u003cstrong\u003estronger antidepressive effect\u003c\/strong\u003e as well as a higher remission rate than the placebo group. (\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e5)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eA mixture of carnosine and its derivative methylcarnosine (anserine) showed positive effects in a further clinical study in healthy elderly people who already showed \u003cstrong\u003emild cognitive impairment\u003c\/strong\u003e, a precursor to dementia. The (methyl-)carnosine group achieved a better score in the \u003c\/span\u003e\u003ci data-mce-fragment=\"1\" style=\"font-family: -apple-system, BlinkMacSystemFont, 'San Francisco', 'Segoe UI', Roboto, 'Helvetica Neue', sans-serif; font-size: 0.875rem;\"\u003eGlobal Clinical Dementia Rating\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e compared to placebo. The improvement was particularly pronounced in carriers of the \"Alzheimer gene\" ApoE4. (\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e6)\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\u003c\/ul\u003e\n\u003ch2 data-mce-fragment=\"1\"\u003e\u003cstrong\u003eL-Carnosine from the PURE range\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eIn our product, we use \u003cstrong\u003epure L-Carnosine\u003c\/strong\u003e in an ideal dosage. As always with PURE products, no additional substances are included. Our L-Carnosine is ideally suited to \u003cstrong\u003ereplenish the body's stores\u003c\/strong\u003e and thus to enjoy the many benefits of carnosine.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eSources\u003c\/span\u003e\u003c\/p\u003e\n\u003col data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e \u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eBaguet, A., Koppo, K., Pottier, A. \u0026amp; Derave, W. Beta-Alanine supplementation reduces acidosis but not oxygen uptake response during high-intensity cycling exercise. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eEur. J. Appl. Physiol. \u003c\/span\u003e\u003c\/i\u003e\u003cb data-mce-fragment=\"1\"\u003e108\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e, 495–503 (2010).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e \u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eHoujeghani, S., Kheirouri, S., Faraji, E. \u0026amp; Jafarabadi, M. A. l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumour necrosis factor-α levels in patients with type 2 diabetes: a double-blind placebo-controlled randomised clinical trial. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eNutr. Res. N. Y. N \u003c\/span\u003e\u003c\/i\u003e\u003cb data-mce-fragment=\"1\"\u003e49\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e, 96–106 (2018).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e \u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eHariharan, R. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eet al.\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e Carnosine supplementation improves glucose control in adults with pre-diabetes and type 2 diabetes: A randomised controlled trial. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eNutr. Metab. Cardiovasc. Dis. \u003c\/span\u003e\u003c\/i\u003e\u003cb data-mce-fragment=\"1\"\u003e34\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e, 485–496 (2024).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e \u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eSiriwattanasit, N., Satirapoj, B. \u0026amp; Supasyndh, O. Effect of Oral carnosine supplementation on urinary TGF-β in diabetic nephropathy: a randomised controlled trial. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eBMC Nephrol. \u003c\/span\u003e\u003c\/i\u003e\u003cb data-mce-fragment=\"1\"\u003e22\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e, 236 (2021).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e \u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eAraminia, B. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eet al.\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e L-Carnosine combination therapy for major depressive disorder: A randomised, double-blind, placebo-controlled trial. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eJ. Affect. Disord. \u003c\/span\u003e\u003c\/i\u003e\u003cb data-mce-fragment=\"1\"\u003e267\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e, 131–136 (2020).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e\u003c\/span\u003e \u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eMasuoka, N. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eet al.\u003c\/span\u003e\u003c\/i\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e Effects of Anserine\/Carnosine Supplementation on Mild Cognitive Impairment with APOE4. \u003c\/span\u003e\u003ci data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003eNutrients \u003c\/span\u003e\u003c\/i\u003e\u003cb data-mce-fragment=\"1\"\u003e11\u003c\/b\u003e\u003cspan data-mce-fragment=\"1\" style=\"font-weight: 400;\" data-mce-style=\"font-weight: 400;\"\u003e, 1626 (2019).\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"edubily®","offers":[{"title":"Default Title","offer_id":50433082360134,"sku":"EDU-150","price":34.5,"currency_code":"CHF","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/L-Carnosin.png?v=1726221732"},{"product_id":"reforce-stainless-steel-shaker","title":"Stainless Steel Shaker","description":"\u003cp\u003eThe Stainless Steel Shaker Reforce is a Swedish innovation from Smartshake. The robust, food-safe stainless steel is extremely durable and hygienic. Stainless steel is one of the most hygienic materials available. With the wide opening and soft corners, it is easy to clean.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eThe shaker enables leak-proof and silent mixing. The included mixer net locks in place, stays sealed and provides perfect results.\u003c\/p\u003e\n\u003cp\u003eThe material used is stainless steel, silicone and transparent PP. The shaker is BPA \u0026amp; DEHP free and tested according to US\/EU food safety standards.\u003c\/p\u003e\n\u003cp\u003eThe bottle capacity is 900 ml.\u003c\/p\u003e\n\u003cp\u003eThe dimensions are: 11.4cm x 9.2cm x 22.8cm\u003c\/p\u003e\n\u003cp\u003eNot suitable for the dishwasher.\u003cbr\u003e\u003c\/p\u003e","brand":"edubily®","offers":[{"title":"Default Title","offer_id":50433083834694,"sku":"EDU-136","price":19.0,"currency_code":"CHF","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/ShakerSchwarz.jpg?v=1726221751"},{"product_id":"pure-macarena","title":"PURE Macarena Capsules","description":"\u003ch2\u003e\n\u003cstrong\u003eWhat's Behind PURE Macarena?\u003c\/strong\u003e \u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/h2\u003e\n\u003cp\u003eAround 20 years ago, Bruce Ames, Professor of Molecular and Cell Biology, and his research team fed old rats the well-known substances Acetyl-L-Carnitine and the powerful antioxidant α-Lipoic Acid. Ames enthusiastically reported the experimental results in a press release:\u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp\u003e\"With both preparations combined, these old rats stood up and danced the Macarena,\" said Ames, also a researcher at the Children's Hospital Oakland Research Institute (CHORI). \"The brain looks better, they are full of energy - everything we examined looks more like that of a young animal.\"\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp\u003e\u003cspan face=\"Verdana, Geneva, sans-serif\" size=\"2\" style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e[\u003c\/span\u003e\u003cspan face=\"Verdana, Geneva, sans-serif\" size=\"2\" style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e\u003ca href=\"https:\/\/newsarchive.berkeley.edu\/news\/media\/releases\/2002\/02\/19_diet.html\" target=\"_blank\"\u003eSource]\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eIn a PNAS article, Ames cited as the reason for this rejuvenation that the two chemicals restore the energy-producing organelles, the \u003cstrong\u003emitochondria\u003c\/strong\u003e, to proper working order. Ames calls the mitochondria the \"weak link of ageing\". There is increasing evidence that deterioration of mitochondrial health is an important cause of ageing. In his view, this deterioration is due to the increased accumulation of destructive free radicals (including by-products of normal metabolism) that inactivate enzymes and other important metabolic molecules.\u003c\/p\u003e\n\u003cp\u003eThe combination therapy aims to \u003cstrong\u003eeliminate these radicals\u003c\/strong\u003e and increase the activity of a damaged enzyme, the \u003cstrong\u003ecarnitine acetyltransferase\u003c\/strong\u003e, which plays a key role in energy metabolism in the mitochondria. Acetyl-L-Carnitine is meant to protect this enzyme, and the elevated carnitine level allows the enzyme to function properly. α-Lipoic Acid, on the other hand, serves to break down oxygen radicals and thus protect the mitochondria from oxidation. (1) (2)\u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp\u003e\"We have significantly reversed the typical decline in overall activity in old rats, achieving the activity levels of middle-aged rats or young adults aged 7 to 10 months,\" said Hagen. \"It's like putting a 75- to 80-year-old person back to middle age. We have only shown short-term effects, but these results provide us with the foundation for a long-term consideration of these matters\".\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\" face=\"Verdana, Geneva, sans-serif\" size=\"2\"\u003e\u003cspan size=\"2\" face=\"Verdana, Geneva, sans-serif\"\u003e[\u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\" face=\"Verdana, Geneva, sans-serif\" size=\"2\"\u003e\u003cspan size=\"2\" face=\"Verdana, Geneva, sans-serif\"\u003e\u003ca href=\"https:\/\/newsarchive.berkeley.edu\/news\/media\/releases\/2002\/02\/19_diet.html\" target=\"_blank\"\u003eSource]\u003c\/a\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eIn a further study by Ames, old rats were again fed Acetyl-L-Carnitine and α-Lipoic Acid, but this time memory function was investigated. They found that the dietary supplement improved both spatial and temporal memory and reduced the amount of oxidative damage to RNA in the hippocampus of the brain, an area important for memory. In electron microscopic images of cells from the hippocampus, mitochondria from old rats that received supplementary nutrition showed less structural decline. (3)\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cspan size=\"2\" face=\"Verdana, Geneva, sans-serif\" style=\"font-family: Verdana, Geneva, sans-serif;\"\u003e(1) Liu, J., Killilea, D.W., and Ames, B.N. (2002) Age-associated Mitochondrial Oxidative Decay: Improvement of Carnitine Acetyltransferase Substrate Binding Affinity and Activity in Brain by Feeding Old Rats Acetyl-L-Carnitine and\/or R-α-Lipoic Acid. Proc. Natl. Acad. Sci. U.S.A. 99, 1876-1881\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\" face=\"Verdana, Geneva, sans-serif\" size=\"2\"\u003e(2) Hagen, T.M., Liu, J., Lykkesfeldt, J., Wehr, C.M., Ingersoll, R.T., Vinarsky, V., Bartholomew, J.C., and Ames, B.N. (2002) Feeding Acetyl-L-Carnitine and Lipoic Acid to Old Rats Significantly Improves Metabolic Function while Decreasing Oxidative Stress. Proc. Natl. Acad. Sci. U.S.A. 99, 1870-1875.\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\" face=\"Verdana, Geneva, sans-serif\" size=\"2\"\u003e(3) Liu, J., Head, E., Gharib, A.M., Yuan, W., Ingersoll, R.T. Hagen, T.M., Cotman, C.W., and Ames, B.N. (2002) Memory Loss in Old Rats is Associated with Brain Mitochondrial Decay and RNA\/DNA Oxidation: Partial Reversal by Feeding Acetyl-L-Carnitine and\/or R-α-Lipoic Acid. Proc. Natl. Acad. Sci. U.S.A. 99, 2356-2361.\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif;\" face=\"Verdana, Geneva, sans-serif\" size=\"2\"\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e","brand":"edubily®","offers":[{"title":"Default Title","offer_id":50433090453830,"sku":"EDU-142","price":38.0,"currency_code":"CHF","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/edubily-product-composing-macarena_1.png?v=1726221934"},{"product_id":"eaa-essentielle-aminosauren-pulver","title":"EAA⁺ Powder – Essential Amino Acids","description":"\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\/\", \n  \"@type\": \"BreadcrumbList\", \n  \"itemListElement\": [{\n    \"@type\": \"ListItem\", \n    \"position\": 1, \n    \"name\": \"Home\",\n    \"item\": \"https:\/\/edubily.de\"  \n  },{\n    \"@type\": \"ListItem\", \n    \"position\": 2, \n    \"name\": \"Products\",\n    \"item\": \"https:\/\/edubily.de\/products\"  \n  },{\n    \"@type\": \"ListItem\", \n    \"position\": 3, \n    \"name\": \"EAA⁺ Powder – Essential Amino Acids\",\n    \"item\": \"https:\/\/edubily.de\/products\/eaa-essentielle-aminosauren-pulver\"  \n  }]\n}\n\u003c\/script\u003e\n\u003cscript type=\"application\/ld+json\"\u003e\n{\n  \"@context\": \"https:\/\/schema.org\/\", \n  \"@type\": \"Product\", \n  \"name\": \"EAA⁺ Powder – Essential Amino Acids\",\n  \"image\": \"https:\/\/edubily.de\/cdn\/shop\/files\/Essentielle_Aminosauren_Zitrone_Frontansicht1500x1500-250KB_1300x.png?v=1716376970\",\n  \"description\": \"The new EAA powder with updated composition, containing Arginine and Histidine, without Sucralose and without B6. Our body builds all protein-based body structures with the help of essential amino acids. Vegan powder in recyclable pouch. 400 g content.\",\n  \"brand\": {\n    \"@type\": \"Brand\",\n    \"name\": \"edubily\"\n  },\n  \"offers\": {\n    \"@type\": \"Offer\",\n    \"url\": \"https:\/\/edubily.de\/products\/eaa-essentielle-aminosauren-pulver\",\n    \"priceCurrency\": \"EUR\",\n    \"price\": \"26\",\n    \"priceValidUntil\": \"2025-11-29\",\n    \"availability\": \"https:\/\/schema.org\/InStock\"\n  },\n  \"aggregateRating\": {\n    \"@type\": \"AggregateRating\",\n    \"ratingValue\": \"4.8\",\n    \"bestRating\": \"5\",\n    \"worstRating\": \"1\",\n    \"ratingCount\": \"224\"\n  }\n}\n\u003c\/script\u003e\n\u003ch1\u003eEAA⁺ Powder – Essential Amino Acids\u003c\/h1\u003e\n\u003cp\u003eWhether before, during or after training – our EAA⁺ Powder is your reliable companion and ideal for your daily challenges.\u003c\/p\u003e\n\u003cp\u003eFinally it's here – our new EAA⁺ Powder!\u003c\/p\u003e\n\u003cp\u003eAfter intensive research and development, we present you with an essential amino acid blend that supports your fitness routine daily.\u003c\/p\u003e\n\u003cp\u003eEssential amino acids are indispensable for your body, especially when it comes to muscle building and recovery.\u003c\/p\u003e\n\u003cp\u003eOur new formula now also contains Arginine and Histidine, making it even more effective. \u003c\/p\u003e\n\u003cp\u003eWithout additional artificial sweeteners like Sucralose, but with the natural sweetness of Stevia, and perfectly soluble thanks to Sunflower Lecithin.\u003c\/p\u003e\n\u003cp\u003eWhether before, during or after training – our EAA\u003cmeta charset=\"utf-8\"\u003e⁺ Powder is your reliable companion and ideal for your daily challenges.\u003c\/p\u003e\n\u003cp\u003eDiscover now how you can unlock your genetic potential!\u003c\/p\u003e\n\u003ch2\u003eWhat Sets Our Essential Amino Acids Apart?\u003c\/h2\u003e\n\u003cp\u003eBe impressed by our new EAA⁺ Blend! \u003c\/p\u003e\n\u003cp\u003eWe have worked hard to offer you a premium product that truly delivers on its promises.\u003c\/p\u003e\n\u003cp\u003eWe have optimised and revised extensively – from now on the new EAA blend, EAA⁺, is available from us.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat's New:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCompletely new amino acid composition\u003c\/li\u003e\n\u003cli\u003eNow with Arginine and Histidine – 10 amino acids instead of 8\u003c\/li\u003e\n\u003cli\u003eNo additional Vitamin B6\u003c\/li\u003e\n\u003cli\u003eNo more Sucralose – pleasantly sweetened with Stevia only\u003c\/li\u003e\n\u003cli\u003eWith Sunflower Lecithin for perfect solubility\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe core question is: What characterises high-quality proteins?\u003c\/p\u003e\n\u003cp\u003eThe answer to this question is that a high proportion of essential amino acids currently determines the quality of a food protein.\u003c\/p\u003e\n\u003cp\u003eFor the composition of our new EAA powder, we therefore used the highest quality food proteins as a model to obtain an ideal EAA blend for humans.\u003c\/p\u003e\n\u003cp\u003eBecause whilst many EAA blends are composed on the basis of theoretical considerations, we wanted to be guided by nature and therefore by high-quality food proteins that humans consume regularly.\u003c\/p\u003e\n\u003cp\u003eWhich amino acids are truly essential is constantly debated in science. \u003c\/p\u003e\n\u003cp\u003eHistidine was considered a semi-essential amino acid until a few years ago, but is now counted amongst the essential amino acids.\u003c\/p\u003e\n\u003cp\u003eReason enough for us to add Histidine to our new blend. \u003c\/p\u003e\n\u003cp\u003eIn addition, Arginine repeatedly shows essential character in studies – which is also why we have added this important amino acid to our product.\u003c\/p\u003e\n\u003ch3\u003eOur New EAA⁺ Powder – These are the 10 Amino Acids!\u003c\/h3\u003e\n\u003cp\u003eIn total, our new EAA⁺ is made up of ten amino acids.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe Functions of Essential Amino Acids:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLeucine, Isoleucine, Valine  \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThese amino acids are components of muscle proteins (actin, myosin, troponin and tropomyosin), which is why they enjoy special popularity as a supplement, particularly in strength sport circles.  \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLysine  \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLysine is extremely important for the formation of collagen proteins, i.e. connective tissue, as it is found there in high concentration in the form of \"Hydroxylysine\".  \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethionine  \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis amino acid serves the body as the starting material for the most important methyl donor in the body, so-called S-Adenosylmethionine.\u003c\/p\u003e\n\u003cp\u003eWith the help of this substance, the body can \"methylate\" genes, that is, switch genes on or off. Methionine thus indirectly serves as a regulator of gene expression.  \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePhenylalanine  \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePhenylalanine is the starting material for the synthesis of neurotransmitters called catecholamines, better known as Dopamine, Noradrenaline and Adrenaline.  \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThreonine  \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThreonine serves the body primarily as the starting material for the synthesis of immune system proteins, specifically the mucus (mucin) of the mucous membranes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTryptophan  \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFrom Tryptophan, the body makes the neurotransmitters Serotonin (\"happiness hormone\") and Melatonin (\"sleep hormone\").\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHistidine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHistidine binds metals well and is therefore a component of e.g. Haemoglobin, the iron-containing blood pigment that can bind oxygen thanks to iron.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eArginine\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe description of the effect of Arginine via nitric oxide earned the Nobel Prize in Medicine in 1998.\u003c\/p\u003e\n\u003cp\u003eArginine is the starting material for the formation of nitric oxide, which regulates vascular function.\u003c\/p\u003e\n\u003cp\u003eAdditionally, Arginine plays an important role in ammonia detoxification (urea cycle), in the immune system and in protein synthesis.\u003c\/p\u003e\n\u003ch2\u003eBuy Amino Acids Powder: Which Preparation is Best?\u003c\/h2\u003e\n\u003cp\u003eIf you want to buy a high-quality amino acids powder, our EAA⁺ Powder is the best choice.\u003c\/p\u003e\n\u003cp\u003eHere are the key unique selling points that make our product special:\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cstrong\u003eNatural Sweetening with Stevia:\u003c\/strong\u003e Unlike many other products, we do not use controversial sweeteners such as Sucralose, Aspartame, Acesulfame K or Saccharin. \u003cbr mit=\"\" stevia=\"\" bieten=\"\" wir=\"\" eine=\"\" nat=\"\" und=\"\" gesunde=\"\"\u003e \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOptimised Amino Acid Composition: \u003c\/strong\u003eOur blend now contains ten instead of eight essential amino acids, including Arginine and Histidine. \u003cbr\u003eThis expansion makes our product even more effective for your health goals.\u003cbr\u003e \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigh Solubility thanks to Sunflower Lecithin: \u003c\/strong\u003eOur powder dissolves excellently in liquid, making application easier and improving the absorption of nutrients in the body.\u003cbr\u003e \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo Unnecessary Additives:\u003c\/strong\u003e We deliberately forgo unnecessary additions and in our nutritional supplements you will find only what is truly needed.\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNatural Inspiration: \u003c\/strong\u003eOur formula is guided by the highest quality natural food proteins, to create an ideal EAA blend that meets the needs of the human body.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003eWith these unique selling points, our EAA⁺ Powder offers you optimal support for your training at every session. \u003c\/p\u003e\n\u003ch2\u003eWhat is the Difference between BCAA and EAA?\u003c\/h2\u003e\n\u003cp\u003eBCAA are Leucine, Isoleucine and Valine. These three are also essential amino acids themselves. \u003c\/p\u003e\n\u003cp\u003eTherefore, a BCAA product supplies only these 3 amino acids, whilst an EAA product contains all BCAAs plus additional essential amino acids\u003c\/p\u003e\n\u003cp\u003eBCAA (branched-chain amino acids) consist of three essential amino acids: Leucine, Isoleucine and Valine. These three amino acids play an important role in muscle building and energy supply during training.\u003c\/p\u003e\n\u003cp\u003eEAA (essential amino acids), on the other hand, comprise ten amino acids that the body cannot produce itself.\u003c\/p\u003e\n\u003cp\u003eAn EAA powder therefore contains the BCAAs plus additional essential amino acids such as Lysine, Methionine and Threonine.\u003c\/p\u003e\n\u003cp\u003eThe main advantage of EAA powder or \u003ca href=\"https:\/\/edubily.de\/products\/lp7-eaa-aminosaeuren-kapseln\" title=\"LP7 Amino Acids \u0026gt;\u0026gt; Buy Vegan Capsules Online\"\u003eEAA Capsules\u003c\/a\u003e over BCAA products lies in the more comprehensive supply of all essential amino acids that are important for numerous body functions.\u003c\/p\u003e\n\u003cp\u003eWhilst BCAAs are primarily relevant for muscle protein synthesis and energy during training, EAAs provide additional support for immune function, neurotransmitter synthesis and general recovery. Therefore, an EAA powder is ideal to ensure more comprehensive nutrient supply and promote athletic performance holistically.\u003cbr\u003e \u003c\/p\u003e","brand":"edubily GmbH","offers":[{"title":"Lemon","offer_id":50433096941894,"sku":"EDU-B-079","price":29.0,"currency_code":"CHF","in_stock":false},{"title":"Sour Apple","offer_id":50433096974662,"sku":"EDU-B-078","price":29.0,"currency_code":"CHF","in_stock":false},{"title":"Passion Fruit","offer_id":53965115261254,"sku":"EDU-B-117","price":29.0,"currency_code":"CHF","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/Essentielle_Aminosauren_Zitrone_Frontansicht1500x1500-250KB.png?v=1726222137"},{"product_id":"pure-glutamin-kapseln","title":"PURE Glutamine Capsules","description":"\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eWhat is Glutamine?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp\u003eGlutamine belongs to those Amino Acids in the body that are present in the greatest quantities.\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eThis is due to the importance of Glutamine for rapidly dividing cells, such as stem cells.\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eGlutamine serves as the ultimate energy source, since Glutamine serves both as fuel and as building material for cells.\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eParticularly significant in this context is Glutamine for immune cells, but also for, for example, mucous membrane cells of the intestine.\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eA high Glutamine requirement thus arises during infections, during sport or other high physical exertion. At the same time, Glutamine plays an important role in building and maintaining skeletal muscle, especially in nutritionally critical situations.\u003c\/p\u003e\n\u003cp\u003eWe obtain Glutamine mainly in the form of Glutamic Acid from food. This exists in the body in dissociated form as a salt, Glutamate. Via\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eGlutamine Synthetase\u003c\/em\u003e, which essentially serves to detoxify ammonia in the body, Glutamate (Glutamic Acid) reacts to form Glutamine.\u003c\/p\u003e\n\u003ch2\u003e\n\u003cstrong\u003eGlutamine Capsules from the PURE Range\u003c\/strong\u003e \u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eOur Glutamine Capsules contain exclusively free L-Glutamine.\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eIt can be stirred into drinks, for example. We refrain from using Glutamine Peptides. For some time it was thought that Peptides had a better effect on muscle, since Glutamine as a free Amino Acid is quickly metabolised by, for example, intestinal cells. This is no longer tenable nowadays. An abundant Glutamine supply will also provide good nourishment to the muscle. Plus:\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eGlutamine Peptides are conventionally obtained from hydrolysed Wheat Protein, which we decidedly reject, since Wheat Peptides are definitely not healthy. \u003c\/strong\u003e\u003c\/p\u003e","brand":"edubily®","offers":[{"title":"Default Title","offer_id":50433101594950,"sku":"EDU-B-114","price":38.0,"currency_code":"CHF","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/L-Glutamin_Kapseln_FrontansichtKopie.png?v=1726222316"},{"product_id":"lp7-eaa-aminosaeuren-kapseln","title":"PURE LP7 Amino Acids Capsules","description":"\u003ch2\u003e\n\u003cstrong\u003eWhat is LP7?\u003c\/strong\u003e \u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/h2\u003e\n\u003cp\u003eLP7 is not an ordinary amino acid mixture and should not be confused with a conventional mixture of essential amino acids, which we already offer \u003ca href=\"https:\/\/edubily.de\/products\/essentielle-aminosauren\"\u003ehere\u003c\/a\u003e. \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eLP7 describes a special composition of seven amino acids: Leucine, Phenylalanine, Lysine, Isoleucine, Histidine, Valine and Tryptophan.\u003c\/strong\u003e The predominant portion consists of Leucine (31%), Phenylalanine (28%) and Lysine (22%). \u003c\/p\u003e\n\u003cp\u003eWe became aware of this mixture in the course of new, highly interesting scientific publications: It was demonstrated in an Alzheimer's animal model that these amino acids had a very positive effect on the brain of the test animals. \u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp\u003e\"These results suggest that these essential amino acids can help maintain balance in the brain and prevent brain decline. Our study is the first to show that certain amino acids can prevent the development of dementia\", say Dr. Hideaki Sato and Dr. Yuhei Takado\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp\u003e– Source: \u003ca href=\"https:\/\/www.sciencedaily.com\/releases\/2021\/10\/211022171458.htm\"\u003eSciencedaily\u003c\/a\u003e \u003c\/p\u003e\n\u003cp\u003eFurthermore, \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7724102\/\"\u003eRCT studies with LP7 in humans\u003c\/a\u003e have already been published, showing that LP7 can have a beneficial effect on cognitive parameters of an older cohort (55 years and older): \u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp\u003eThe current results suggest that taking the seven essential amino acids leads to an improvement in attention, cognitive flexibility and psychosocial functioning, which is expected to prevent cognitive decline.\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp\u003eAnd so the first prototype of this product goes on sale with us, with the expectation that various further studies will follow that can confirm the results. In the meantime, our customers can test and try the mixture themselves. \u003c\/p\u003e\n\u003cp\u003eBecause the product is part of our PURE range, we have deliberately avoided using any additives – therefore \u003cstrong\u003ethe capsules\u003c\/strong\u003e contain exclusively the seven amino acids that represent LP7 in the correct ratio. \u003c\/p\u003e","brand":"edubily®","offers":[{"title":"Default Title","offer_id":50433102217542,"sku":"EDU-B-116","price":39.0,"currency_code":"CHF","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/PURE_LP7_Aminosauren_Frontansicht1500x1500.png?v=1726222360"},{"product_id":"pure-citrullin-malat-kapseln","title":"PURE Citrulline-Malate Capsules","description":"\u003ch2\u003e\n\u003cstrong\u003eWhat is Citrulline-Malate?\u003c\/strong\u003e \u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/h2\u003e\n\u003cp\u003eCitrulline is an amino acid, whose name is derived from \u003cem\u003ecitrullus\u003c\/em\u003e, the Latin word for watermelon. The existence of the amino acid has been known since the late 19th century – however, it was first isolated from watermelons and described in detail at the beginning of the 20th century by Japanese researchers. Watermelons are considered to this day an important and natural source of citrulline. \u003c\/p\u003e\n\u003cp\u003eFundamentally, citrulline is an important intermediate in the urea cycle, the pathway through which mammals excrete ammonia by converting it into urea.\u003c\/p\u003e\n\u003cp\u003eCitrulline also arises as a by-product of the enzymatic production of nitric oxide (NO) from the amino acid arginine, catalysed by nitric oxide synthase. In this way, citrulline also serves the body as a starting material for the formation of NO (nitric oxide), since it is converted back into arginine via the urea cycle. \u003c\/p\u003e\n\u003cp\u003eWith regard to citrulline supplementation, it was shown using a mouse model that citrulline raises arginine levels even more than arginine itself. This is because arginine undergoes extensive metabolism by intestinal cells and only a fraction of it enters the bloodstream. Citrulline, however, can be converted directly into arginine to a large extent, which in turn serves NO synthesis in the body. \u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp\u003eConclusions: Citrulline supplementation is more efficient at increasing arginine availability than arginine supplementation itself in mice.\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp\u003e– \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5368575\/\" data-mce-href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5368575\/\"\u003eSource\u003c\/a\u003e \u003c\/p\u003e\n\u003cp\u003eCitrulline-malate is a special form of citrulline bound to malic acid, which gives apples their characteristic tartness. The compound gained greater recognition about 20 years ago when a human study, \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12145119\/\" data-mce-href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12145119\/\"\u003epublished in the British Journal of Sports Medicine\u003c\/a\u003e, demonstrated using magnetic resonance spectroscopy that the administration of citrulline-malate improved muscle energy production via mitochondria. \u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp\u003eBoth the rate of oxidative ATP production in muscles during training and the rate of PCr recovery after training increase in participants who received citrulline\/malate for 15 days. This positive effect of citrulline\/malate at the oxidative level can be mediated by malate, an intermediate of the tricarboxylic acid cycle.\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp\u003eThe researchers hypothesised that this is not due per se to citrulline, but rather to malic acid (malate), which can be converted into the citric acid cycle – the citric acid cycle being an essential component of muscle energy production. \u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp\u003eMalate is dehydrated to oxaloacetate in the citric acid cycle, the concentration of which is one of the most important control factors for the rate of aerobic ATP production.\u003cbr\u003e\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003ch2\u003eThe Effect of Citrulline Malate\u003cbr\u003e\n\u003c\/h2\u003e\n\u003cp\u003eTo this day, the effect of citrulline-malate is being studied specifically in the context of strength and endurance sport – with mixed results. No clear intake recommendation for athletes – such as with \u003ca href=\"https:\/\/edubily.de\/products\/creatin-pulver\" data-mce-href=\"https:\/\/edubily.de\/products\/creatin-pulver\"\u003ecreatine\u003c\/a\u003e – can be derived from the results. \u003c\/p\u003e\n\u003cp\u003eNevertheless, citrulline-malate remains one of the more interesting supplements, with possibly ergogenic effects, especially in the context of high-intensity training sessions and competitions.\u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp\u003eThese data suggest that taking citrulline-malate before competition can improve the performance of tennis players. However, this study used a controlled laboratory environment, so an investigation of the direct application to performance on the tennis court should be considered.\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp\u003e– \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27017895\/\" data-mce-href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27017895\/\"\u003eSource of the RCT study from 2016\u003c\/a\u003e \u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eWe offer citrulline capsules in the context of our PURE series. Due to production reasons, we had to resort to an excipient, silica. 5 capsules provide 2 g citrulline with just under 3 g citrulline-malate. \u003c\/p\u003e","brand":"edubily®","offers":[{"title":"Default Title","offer_id":50433103102278,"sku":"EDU-B-115","price":40.0,"currency_code":"CHF","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/PURE_Citrullin-Malat_Frontansicht1500x1500.png?v=1726222379"},{"product_id":"n-acetyl-l-cystein","title":"PURE N-Acetyl-L-Cysteine (NAC)","description":"\u003ch2\u003e\n\u003cstrong\u003eWhat is N-Acetyl-L-Cysteine (NAC)?\u003c\/strong\u003e \u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/h2\u003e\n\u003cp\u003eL-Cysteine is a semi-essential amino acid, which means it can fundamentally be produced by the body itself (mainly from methionine), although supplementation may be advisable during certain life phases.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is special about cysteine is that it is a so-called sulphur-containing amino acid.\u003c\/strong\u003e That is, it contains sulphur, specifically at the terminal end as a \u003cem\u003esulphydryl group\u003c\/em\u003e. The significance of cysteine for the body stems precisely from this: this reactive sulphur group can, for example, react with another sulphur group of a cysteine in another protein or another protein part and thus build \u003cem\u003edisulphide bonds\u003c\/em\u003e.\u003c\/p\u003e\n\u003ch2\u003eThe Function of N-Acetyl-L-Cysteine\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eThis in turn provides stress tolerance, tensile strength, and also the function of various proteins in the body.\u003c\/strong\u003e An excellent example of this is the structural protein keratin, which in mammals is found in large proportions in hair, fingernails and toenails, claws, hooves, horns and nasal horns. The fibres are all the stiffer, the more strongly their components are cross-linked through disulphide bonds via L-cysteine. So keratin in horns and claws contains more disulphide bonds than that in wool and hair.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHowever, the sulphydryl group of cysteine also reacts with metals.\u003c\/strong\u003e Therefore, for example, zinc in proteins is often bound to cysteine. Due to this property, cysteine is also a main component of the body's own antioxidant glutathione. \u003cstrong\u003eGlutathione can, for example, react with heavy metals via the sulphydryl group, bind them and thereby detoxify them.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eN-Acetyl-L-Cysteine (NAC) is an acetylated form of cysteine.\u003c\/strong\u003e The antioxidant, anti-inflammatory and mucus-dissolving properties of NAC are the reason for the use of NAC in higher doses as a medicine (e.g. ACC® akut). After ingestion, NAC is also converted to L-cysteine, which in turn is partially converted to glutathione. \u003cstrong\u003eHowever, NAC is more stable than free L-cysteine and has much lower toxicity, making it safer and more effective for increasing cysteine levels in the body.\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003e\n\u003cstrong\u003eThe edubily® NAC\u003c\/strong\u003e \u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/h2\u003e\n\u003cp\u003eOur NAC capsules contain exclusively N-Acetyl-L-Cysteine. It is safely dosed and can be used for daily nutritional supplementation, that is for increasing cysteine levels in the body. If you have any questions before your purchase, please feel free to contact us at any time.\u003c\/p\u003e","brand":"edubily®","offers":[{"title":"Default Title","offer_id":50433110180166,"sku":"EDU-099","price":21.0,"currency_code":"CHF","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/edubily-product-acetylcystein.png?v=1726222583"},{"product_id":"citrullin-plus","title":"Citrulline Plus","description":"\u003ch2\u003e\n\u003cstrong\u003eWhat is Nitric Oxide?\u003c\/strong\u003e \u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eIn 1998, the Nobel Prize in Physiology or Medicine was awarded to American scientists Ignarro, Furchgott and Murad. \u003cstrong\u003eThey discovered and described a gas that is produced and released in blood vessel walls and regulates vessel function: Nitric Oxide, or NO for short.\u003c\/strong\u003e To better understand the effect of NO in the body, one need only think of the famous blue pills for improved performance, which inhibit NO breakdown and thereby stimulate blood circulation. Heart medications work in a similar way, which are based on organic nitrates or nitro-glycerin. Here too, the strongly released Nitric Oxide is intended to dilate the arteries and promote blood circulation.\u003cspan class=\"Apple-converted-space\" data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg style=\"float: none;\" alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0008\/7415\/1991\/files\/NY_Times_Nobelpreis_Ignarro_NO_600x600.png?v=1649937864\"\u003e\u003c\/div\u003e\n\u003cp style=\"text-align: center;\" data-mce-fragment=\"1\"\u003e\u003cem\u003eThe Nobel Prize in Physiology or Medicine was awarded in 1998 to three Americans who discovered NO and described its functions in the body in greater detail. Source: \u003ca href=\"https:\/\/www.nytimes.com\/1998\/10\/13\/us\/three-americans-awarded-nobel-for-discoveries-of-how-a-gas-affects-the-body.html\"\u003eNY Times\u003c\/a\u003e. \u003c\/em\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eNitric Oxide is produced in the endothelial layer of blood vessels and causes dilation or relaxation of smooth vessel muscle. Medical science has published impressive results on NO over the past 10–20 years. \u003cstrong\u003eThus, Nitric Oxide generally promotes vessel health – moreover, a good NO level is a prerequisite for blood vessels to remain healthy at all.\u003c\/strong\u003e A fall in NO levels, which is typically found in the context of Western, that is to say modern lifestyles, causes blood vessels to become dysfunctional, referred to as \u003cem\u003eendothelial or vascular dysfunction \u003c\/em\u003e(\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32172815\/\"\u003eCyr et al. 2020\u003c\/a\u003e)\u003cem\u003e.\u003c\/em\u003e Long-term consequences include arteriosclerosis or other vascular diseases.\u003cspan class=\"Apple-converted-space\" data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eIn recent years, it has additionally been discovered that Nitric Oxide has very, very far-reaching effects on the body. \u003cstrong\u003eThus, it regulates the function of the immune system, and moreover that of cellular energy metabolism.\u003c\/strong\u003e That is, vessel health and general health and in particular the health of energy metabolism are closely linked to one another.\u003cspan class=\"Apple-converted-space\" data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp data-mce-fragment=\"1\"\u003eNitric Oxide (NO) is a signalling molecule that is synthesised in animals by NO synthase from L-Arginine. There is increasing evidence that NO regulates the metabolism of energy substrates in mammals. \u003cbr\u003e\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp data-mce-fragment=\"1\"\u003e(\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23553707\/\"\u003eDai et al. 2013\u003c\/a\u003e) \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eNO discoverer and Nobel laureate Louis Ignarro wrote the book „\u003cem\u003eNO More Heart Disease: How Nitric Oxide Can Prevent--Even Reverse--Heart Disease and Strokes\"\u003c\/em\u003e based on these findings and his research. Because: \u003cstrong\u003eNO can be positively influenced by lifestyle factors.\u003c\/strong\u003e Thus, the starting substance for the formation of NO is the amino acid Arginine.\u003c\/p\u003e\n\u003ch2\u003e\n\u003cstrong\u003eWhy Citrulline?\u003c\/strong\u003e \u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eArginine is, however, rapidly metabolised with supplementation. Citrulline, on the other hand, bypasses these effects and increases the arginine level in the blood more strongly than arginine itself. Generally speaking, some substances that can be ingested through food have a positive influence on the modulation of NO levels. \u003c\/p\u003e\n\u003cblockquote\u003e\n\u003cp data-mce-fragment=\"1\"\u003eL-Citrulline supplementation led to an increase in arginine flux and to a stronger increase in arginine concentration in the plasma than arginine supplementation itself. Whilst citrulline escaped first-pass metabolism, 70% of the supplemented arginine disappeared before it reached the peripheral circulation.\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003cp data-mce-fragment=\"1\"\u003e(\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5368575\/\"\u003eMarini et al. 2017\u003c\/a\u003e) \u003c\/p\u003e\n\u003ch2\u003e\n\u003cstrong\u003eWhat sets edubily®-Citrulline plus apart\u003c\/strong\u003e \u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/h2\u003e\n\u003cp data-mce-fragment=\"1\"\u003eOur product is a delicious, refreshing powder that contains all the necessary cofactors, including Vitamin C from Acerola extract, Citrulline in the well-known malate form (Citrulline malate), Folic acid in two forms (for optimal effect), bioactive Vitamin B12, Glycine, \u003ca href=\"https:\/\/edubily.de\/products\/taurin\"\u003eTaurine\u003c\/a\u003e and the plant compound \u003ca href=\"https:\/\/edubily.de\/products\/granatapfel-extrakt-1\"\u003ePomegranate Extract\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThis premium blend of exciting ingredients not only tastes outstanding, but has been appreciated by thousands of customers for many years – this experience confirms that we have created a unique product here. \u003cbr\u003e\u003c\/p\u003e","brand":"edubily®","offers":[{"title":"Default Title","offer_id":50433116668230,"sku":"EDU-B-004","price":27.5,"currency_code":"CHF","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/Citrullin_plus_Frontansicht_1500x1500-250KB.png?v=1726222731"},{"product_id":"l-glutamin-pulver","title":"PURE L-Glutamine Powder","description":"\u003cp\u003eGlutamine is considered the most abundant amino acid in the human body.\u003c\/p\u003e\n\u003cp\u003eThe reason for this is that glutamine serves as the ultimate energy supplier for rapidly dividing cells.\u003c\/p\u003e\n\u003cp\u003eWe deliberately avoid glutamine peptides derived from wheat protein and instead rely on vegan, free L-glutamine.\u003c\/p\u003e\n\u003cp\u003eOur L-glutamine powder is available in a 500 g bag and belongs to our PURE range, which means it is free from additives and consists exclusively of L-glutamine.\u003c\/p\u003e\n\u003ch2\u003eWhat distinguishes our glutamine powder?\u003c\/h2\u003e\n\u003cp\u003eOur L-glutamine powder is derived from plant-based fermentation. We deliberately avoid glutamine peptides made from wheat protein to be able to offer a pure and vegan product.\u003c\/p\u003e\n\u003cp\u003eGlutamine is part of our \u003ca title=\"Pure Series\" href=\"https:\/\/edubily.de\/collections\/pure-serie\"\u003ePURE Series\u003c\/a\u003e, which means that only what is stated on the packaging is included: 100 % pure L-glutamine.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e100 % free L-glutamine\u003c\/strong\u003e\u003cbr\u003eOur L-glutamine powder comes from plant-based fermentation and is therefore vegan. It can be easily stirred into drinks and is therefore very simple to integrate into everyday life.\u003cbr\u003e \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo gluten source\u003c\/strong\u003e\u003cbr\u003eWe completely avoid glutamine peptides from wheat protein. This makes our product gluten-free and also suitable for people with gluten intolerance.\u003cbr\u003e \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNo additives \u0026amp; flavourings\u003c\/strong\u003e\u003cbr\u003eOur L-glutamine powder contains no flavourings or other additives. It consists of 100 % pure L-glutamine and is therefore free from any artificial ingredients.\u003cbr\u003e \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeavy metals analysed\u003c\/strong\u003e\u003cbr\u003eWe have our L-glutamine powder regularly analysed by independent laboratories for heavy metals, including arsenic.\u003cbr\u003e\u003cbr\u003eThe results of these tests are available in our database, so you can be sure that you are using a safe and high-quality product.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThese properties make our L-glutamine powder an ideal choice if you are looking for high-quality, pure glutamine for your nutritional supplement.\u003c\/p\u003e\n\u003cp\u003eWhether you want to buy L-glutamine to support your gut or use L-glutamine powder for your wellbeing – you will find a product that meets the highest quality standards with us.\u003c\/p\u003e\n\u003ch2\u003eWhat is L-glutamine?\u003c\/h2\u003e\n\u003cp\u003eGlutamine is one of the amino acids that is most abundant in the human body.\u003c\/p\u003e\n\u003cp\u003eThis amino acid plays a central role as an energy supplier for rapidly dividing cells, such as stem cells.\u003c\/p\u003e\n\u003cp\u003eGlutamine serves both as fuel and as a building block for cells, making it an indispensable part of human metabolism.\u003c\/p\u003e\n\u003cp\u003eGlutamine is particularly important for immune cells and intestinal mucous membrane cells. These cells use glutamine as their preferred energy source, which supports their function and regeneration.\u003c\/p\u003e\n\u003cp\u003eDue to these properties, glutamine is of high relevance for the gut and the immune system.\u003c\/p\u003e\n\u003ch3\u003eGlutamine as an amino acid and its significance\u003c\/h3\u003e\n\u003cp\u003eGlutamine is not just a simple amino acid, but fulfils numerous important functions in the body. It is crucial for protein synthesis, which supports the building and maintenance of muscle mass.\u003c\/p\u003e\n\u003cp\u003eFurthermore, it plays a role in regulating the acid-base balance and nitrogen balance in the body.\u003c\/p\u003e\n\u003ch3\u003eIncreased glutamine requirement\u003c\/h3\u003e\n\u003cp\u003eDuring training or stress, the need for glutamine increases.\u003c\/p\u003e\n\u003cp\u003eIn such phases, the body may not be able to produce enough glutamine itself, which is why supplementation can be helpful.\u003c\/p\u003e\n\u003cp\u003eEspecially during intense physical exertion or in the recovery phase after illness, taking L-glutamine powder can help promote recovery and wellbeing.\u003c\/p\u003e\n\u003ch3\u003eGlutamine for the gut\u003c\/h3\u003e\n\u003cp\u003eGlutamine is particularly important for the gut. It supports the integrity of the intestinal barrier and promotes the regeneration of intestinal cells.\u003c\/p\u003e\n\u003cp\u003eThere is also evidence that glutamine can counteract inflammatory processes, which could play a role in Leaky Gut Syndrome, for example.\u003c\/p\u003e\n\u003ch3\u003eL-glutamine as a dietary supplement\u003c\/h3\u003e\n\u003cp\u003eBuying L-glutamine can therefore be a sensible decision to ensure that your body is always adequately supplied with this important amino acid.\u003c\/p\u003e\n\u003cp\u003eOur PURE L-glutamine powder is an excellent choice if you are looking for a pure, additive-free supplement.\u003c\/p\u003e\n\u003cp\u003eIt provides you with a high-quality source of this essential amino acid.\u003c\/p\u003e\n\u003ch2\u003eHow much glutamine do we need?\u003c\/h2\u003e\n\u003cp\u003eA high glutamine requirement arises from infections, sport or other intense physical exertion.\u003c\/p\u003e\n\u003cp\u003eIn such situations, the body's need for glutamine increases significantly to meet the demands of the immune system and muscles.\u003c\/p\u003e\n\u003cp\u003eGlutamine plays an important role in building and maintaining skeletal muscle, especially in nutritionally critical situations.\u003c\/p\u003e\n\u003cp\u003eWe mainly obtain glutamine in the form of glutamic acid through food. In the body, this exists in dissociated form as a salt, glutamate.\u003c\/p\u003e\n\u003cp\u003eVia glutamine synthetase, which essentially serves to detoxify ammonia in the body, glutamate (glutamic acid) is converted to glutamine.\u003c\/p\u003e\n\u003cp\u003eDuring intense physical activity or stress, the body's own production of glutamine may not be sufficient to meet the increased demand. In such cases, taking glutamine as a dietary supplement can be beneficial.\u003c\/p\u003e\n\u003cp\u003eEspecially in the PURE form, like our L-glutamine powder, which comes from plant-based fermentation, you can be sure of getting a pure and high-quality product.\u003c\/p\u003e\n\u003cp\u003eL-glutamine supplementation can be an effective method to ensure that your body is adequately supplied during times of increased strain.\u003c\/p\u003e\n\u003ch2\u003eBuy L-glutamine: Glutamine powder from the PURE range\u003c\/h2\u003e\n\u003cp\u003eOur glutamine powder contains exclusively free L-glutamine. It can be wonderfully stirred into drinks and is therefore very flexible to use.\u003c\/p\u003e\n\u003cp\u003eWe deliberately avoid glutamine peptides. For some time, it was assumed that peptides had a better effect on muscles because glutamine, as a free amino acid, is quickly metabolised by intestinal cells, for example.\u003c\/p\u003e\n\u003cp\u003eThis assumption is no longer valid today. An abundant glutamine intake will also adequately supply the muscles without the need for glutamine peptides.\u003c\/p\u003e\n\u003cp\u003ePlus: Glutamine peptides are conventionally derived from hydrolysed wheat protein, which we firmly reject because wheat peptides are definitely not healthy.\u003c\/p\u003e\n\u003cp\u003eOur L-glutamine powder is free from such peptides and offers you 100 % pure and gluten-free glutamine from plant-based fermentation.\u003c\/p\u003e","brand":"edubily®","offers":[{"title":"Default Title","offer_id":50433127842118,"sku":"EDU-046","price":21.0,"currency_code":"CHF","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/L-Glutamin_Pulver_Frontansicht-250KB.png?v=1726222873"},{"product_id":"l-carnitin","title":"PURE L-Carnitine Capsules","description":"\u003ch2\u003e\u003cb\u003eWhat is L-Carnitine? \u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eL-Carnitine (lat.: caro, carnis = flesh) is a substance of immense importance for metabolism ('vitamin-like'), which we obtain mainly through food despite the body synthesising approximately 10 to 20 mg per day.\u003c\/strong\u003e Carnitine is found mainly in red meat – lamb, beef and mutton can contain 100 mg per 100 g of meat. Those on mixed diets consume approximately 50 mg per day through food, whilst vegetarians' intake can drop to sometimes under 5 mg per day. \u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eFor the body's own synthesis, it requires the amino acids lysine and methionine, as well as Vitamin C, Vitamin B3, Vitamin B6 and iron. \u003cstrong\u003eThe body's synthesis capacity is sufficient on a mixed diet to prevent deficiency symptoms.\u003c\/strong\u003e However, a deficiency of the aforementioned substances can significantly reduce the amount of synthesised carnitine. \u003cstrong\u003ePlant-based, meat-free diets can also quickly cause serious deficiency symptoms.\u003c\/strong\u003e Carnitine is known as an essential cofactor for metabolising fatty acids as energy carriers. Indeed, mitochondria require carnitine to transport long-chain fatty acids via \u003cem\u003ecarnitine palmitoyltransferase\u003c\/em\u003e across the mitochondrial membrane. Only then can they serve as energy carriers. \u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003eDoes L-Carnitine Increase Fat Burning?\u003c\/h2\u003e\n\u003cp\u003eWhether carnitine can increase fat burning in this way has been the subject of heated debate for years. Conclusive data on this does not exist. \u003cstrong\u003eHowever, Müller et al. demonstrated nearly 20 years ago using radioactively labelled fatty acids that carnitine supplementation increased the oxidation of these fatty acids by 30 %\u003c\/strong\u003e (1). Fairly recent genetic research also shows that Europeans often have mutations in the carnitine transporter gene (OCTN2), which may increase the carnitine requirement in those people who carry these polymorphisms (2).\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e(1) Müller D et al. (2002) Effects of oral L-carnitine supplementation on in vivo long-chain fatty acid oxidation in healthy adults. Metabolism 51(11):1389–1391\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e(2) Urban T et al. (2006). Functional Genetic Diversity in the High-Affinity Carnitine Transporter OCTN2 (SLC22A5). Molecular Pharmacology, 70(5), 1602-1611. doi: 10.1124\/mol.106.028126\u003c\/em\u003e\u003c\/p\u003e\n\u003ch2\u003e\u003cb\u003eL-Carnitine Capsules from the PURE Range\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/b\u003e\u003c\/h2\u003e\n\u003cp\u003eOur capsules contain Acetyl-L-Carnitine. Here carnitine is bound to an acetyl group, which is also found in the body in this form. The advantage is that this compound is said to have its own biological activity, but far more important: this compound is very well tolerated, extremely bioavailable and the carnitine proportion in the compound is very high because the acetyl group is small. This allows us to achieve optimal efficiency: the product is very well tolerated and ideally dosed.\u003cspan class=\"Apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/p\u003e","brand":"edubily®","offers":[{"title":"Default Title","offer_id":50433218117958,"sku":"EDU-071","price":19.0,"currency_code":"CHF","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/edubily-carnitin-v2.png?v=1726223394"},{"product_id":"edu_basic","title":"edu basic","description":"What is \u003cem\u003eedu_basic\u003c\/em\u003e?\n\u003cp\u003eThe edubily® \u003cem\u003eedu_basic \u003c\/em\u003e, in a slightly modified form, was the very first dietary supplement we brought to market in 2015 and the predecessor to our current product \u003cem\u003eCitrulline Plus \u003c\/em\u003e(For more on the specific product background \u003ca href=\"https:\/\/edubily.de\/products\/citrullin-plus\"\u003eon the product page\u003c\/a\u003e). \u003c\/p\u003e\n\u003cp\u003eWe offer this classic product from time to time in limited quantities, which is each time accompanied by outstanding feedback – which in turn motivates us to relaunch it periodically.\u003c\/p\u003e\n\u003cp\u003eThe product essentially consists of amino acids (L-Citrulline Malate, Arginine, Glycine and Tryptophan) and amino acid derivatives (Taurine), which are supplemented with methylsulfonylmethane (MSM) as a sulphur supplier.\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eedu_basic \u003c\/em\u003eis designed as a \"lifestyle support\" to broadly target many biochemical and physiological mechanisms of the body and compensate for weaknesses, thereby encompassing both the cardiovascular system, energy metabolism and sleep.\u003c\/p\u003e\n\u003cp\u003eAs always: Limited Edition. Only for a short time. \u003c\/p\u003e","brand":"edubily®","offers":[{"title":"Default Title","offer_id":50433218150726,"sku":"EDU-074","price":34.5,"currency_code":"CHF","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0855\/4030\/7270\/files\/mockup-edubasic_1.png?v=1726223401"}],"url":"https:\/\/www.edubily.ch\/en\/collections\/aminosauren.oembed","provider":"edubily Schweiz ","version":"1.0","type":"link"}